EHMT2 INACTIVATION IN PANCREATIC EPITHELIAL CELLS SHAPES THE TRANSCRIPTIONAL LANDSCAPE AND INFLAMMATION RESPONSE OF THE WHOLE PANCREAS

Ehmt2 inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas

Introduction: The Euchromatic Histone Methyl Transferase Protein 2 (EHMT2), also known as G9a, deposits transcriptionally repressive chromatin marks that play pivotal roles in the maturation and homeostasis of multiple organs.Recently, we have shown that Ehmt2 inactivation in the mouse pancreas alters growth and immune gene expression networks, ant

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Whole Genome Analysis of a Single Scottish Deerhound Dog Family Provides Independent Corroboration That a SGK3 Coding Variant Leads to Hairlessness

The breeds Pre-order of domestic dog, Canis lupus familiaris, display a range of coat types with variation in color, texture, length, curl, and growth pattern.One trait of interest is that of partial or full hairlessness, which is found in a small number of breeds.While the standard for some breeds, such as the Xoloitzcuintli, requires sparse hair

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Framework for treating non-Linear multi-term fractional differential equations with reasonable spectrum of two-point boundary conditions

In this work, a novel bio-inspired meta-heuristic framework is presented for HF Ballasts the assessment of linear and non-linear multi-term fractional differential equations (MFDEs) based on the idea of residual power series method (RPSM) in amalgamation with the bat algorithm (BATA) which, mimics the echolocation behavior of the foraging bats.The

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